The hydrogenation of methyl and ethyl (2E)-3-[5-(azidomethyl)-2,2-diethyl-1,3-dioxolan-4-yl]-2-methylprop-2-enoates over palladium catalyst afforded the expected reduction products.”
“Purpose:
To assess modifiable clusters of cardiovascular risk factors and patterns of antihypertensive drugs use as well as identify clinical characteristics associated with blood pressure control in Jordanians.
Methods: A cross-sectional observational study Screening Library concentration was conducted in cardiology outpatient clinics at two hospitals in Amman, Jordan. Outcomes studied were prevalence of cardiovascular risk factors, patterns of antihypertensive medication use, rate of blood pressure control and factors associated with such control.
Results: The number of concomitant medical conditions was high: diabetes mellitus (51 %), dyslipidemia (82 %), coronary artery disease (71 %), history of acute coronary syndrome (37 %) or coronary revascularization (64 %). Hypertension was controlled in 44 % of patients. Average number of antihypertensive medications was 2.38 +/- 1.21. The most commonly prescribed monotherapy medications were beta-blockers (48 %), followed by angiotensin-converting enzyme inhibitors (ACEIs) with 28 % and angiotensin II receptor blockers MG 132 (ARBs) with 23 %. Among all patients, beta-blockers (67 %) were also the most prescribed,
followed by ACEIs (47 %) and ARBs (41%). Multivariate logistic regression analysis revealed inverse association between BP control and the presence of diabetes mellitus.
Conclusion: There is inadequate cardiovascular risk assessment and control of blood pressure in hypertensive patients in Jordan. Several practical measures need to be taken urgently to mitigate these deficiencies.”
“Background: Different types of devices are available and the choice about which to use depends on various factors: cost, physical characteristics, performance, and the validity and intra- and interinstrument Lonafarnib in vivo reliability. Given the large number of studies that have used uniaxial or triaxial devices, it is of interest to know whether the different devices give similar information
about PA levels and patterns. The aim of this study was to compare physical activity (PA) levels and patterns obtained simultaneously by triaxial accelerometry and uniaxial accelerometry in adolescents in free-living conditions.
Methods: Sixty-two participants, aged 13-16 years, were recruited in this ancillary study, which is a part of the Healthy Lifestyle in Europe by Nutrition in Adolescence (HELENA). All participants wore a uniaxial accelerometer (ActiGraph GT1M (R), Pensacola, FL) and a triaxial accelerometer (RT3 (R), Stayhealthy, Monrovia, CA) simultaneously for 7 days. The patterns were calculated by converting accelerometer data output as a percentage of time spent at sedentary, light, moderate, and vigorous PA per day. Analysis of output data from the two accelerometers were assessed by two different tests: Equivalence Test and Bland & Altman method.