66, 95% CI 0.74-3.74). The meta-analysis indicated the significant association of +869T/C, but not +915G/C polymorphism with hypertension susceptibility. However, given the limited sample size, the associations warrant further investigation.”
“Non-invasive temperature measurement of tissues deep inside the body has great potential for clinical applications, such as temperature monitoring during thermal therapy and early diagnosis of diseases. We developed a novel method for both temperature estimation and thermal mapping that uses ultrasound

B-mode radio-frequency data. The proposed method is a hybrid that combines elements of physical and statistical models to achieve higher precision and resolution of temperature Oligomycin A solubility dmso variations and distribution. We propose a dimensionless combined index (CI) that combines the echo shift differential and signal intensity difference

with a weighting factor relative to the distance from the heat source. In vitro experiments verified that the combined index has a strong linear relationship with temperature variation and can be used to effectively estimate temperature with an average relative error <5%. This algorithm provides an alternative for imaging guidance-based techniques during thermal therapy JQ1 research buy and could easily be integrated into existing ultrasound systems. (C) 2014 World Federation for Ultrasound in Medicine & Biology.”
“Purpose. – Surgery is the treatment of choice for localized uterine sarcomas. We conducted a retrospective study to define prognostic factors.\n\nPatients and methods. – We studied 111 cases of patients treated by adjuvant radiotherapy for uterine sarcoma in seven French centers. The median decline was 31 months. We conducted a univariate analysis to identify factors correlated with local recurrence. The statistically significant factors were studied in multivariate analysis by Cox model.\n\nResults. – The median dose of external beam radiotherapy

was 45 Gy. Forty-three percent of patients had vaginal vault brachytherapy and 21% chemotherapy. Only 6.3% of patients had complications of acute grade III and 8.1% of long-term sequelae of radiotherapy. The survival rate at 5 years was 74.6%. They noted 12.6% of isolated selleck inhibitor locoregional recurrences, against 29.7% for distant recurrences, 80% were pulmonary. Factors correlated with the risk of locoregional relapse were menopausal status (P=0.045) and surgical margins suspicious or not healthy (P=0.0095). The chemotherapy did not improve overall survival or disease free survival but the numbers were low.\n\nConclusion. – The postoperative radiotherapy provides good local control in this disease. Brachytherapy is sometimes done, but it does not improve local control. Chemotherapy is not a standard localized stage but the rate of metastatic recurrence calls for the development of strategies involving systemic treatment with radiotherapy. (C) 2010 Societe francaise de radiotherapie oncologique (SFRO). Published by Elsevier Masson SAS.