Although most of the literature consists of occasional case reports Savolitinib nmr or small case series, we searched for literature published between 1983 and 2012 using PubMed and Web Japan Medical Abstracts Society and found 37 reported

cases of teenage patients (ages 13 through 19) with intestinal malrotation (Table 1). Twenty patients were male and seventeen were female. The diagnosis could be made by radiographic studies in all these patients. Patients presented with a variety of gastrointestinal disorders. Abdominal pain was the most frequent symptom (30/37). Other symptoms were nausea, feeding intolerance, reflux, and respiratory problems. The Ladd procedure was performed on 27 patients; on 12 patients the procedure was conducted laparoscopically. Table 1 Reported cases of intestinal malrotaion (13–19 years old) Year Author Journal Age Gender Symptoms Surgery 1991 Ko, et al. Jpn J Surg (in Wortmannin order Japanese) 19 F abdominal distention Ladd procedure 1992 Lal, et al. Indian J Gastroenterol

17 F abdominal pain, vomiting gastrojejunostomy, vagotomy 1994 Pelucio, et al. Am J Emerg Med 15 M abdominal pain Ladd procedure 1997 Kimura, et al. Jpn J Clin Surg (in Japanese) 16 M vomiting Ladd procedure 1997 Ishida, et al. J Jpn Soc Pediatr Surg (in Japanese) 13 F abdominal pain, vomiting Ladd procedure 1997 Yahata, et al. Surg Laparosc Endosc 17 F abdominal pain laparoscopic Ladd procedure 1998 Yokota, et al. Kesennuma Hosp Medical J (in Japanese) 15 F abdominal pain Ladd procedure 1999 Kang, et al. J Jpn Soc Pediatr Surg (in Japanese) 16 M abdominal pain, vomiting Ladd procedure 1999 Yamashita, et al. Surg Endosc Selleckchem eFT-508 13 F vomiting laparoscopic Ladd procedure 2000

Walsh, et al. J Pediatr Surg 13 F abdominal pain laparoscopic Ladd procedure 2001 Horiba, et al. J Jpn Clin Surg (in Japanese) 17 M vomiting Ladd procedure 2003 Tsumura, et al. Surg Endosc 15 F abdominal pain laparoscopic Ladd procedure 2003 Singer, et al. J Am Coll Surg 19 M abdominal pain, vomiting Ladd procedure 2004 Tseng, BCKDHB et al. JBR-BTR 14 F abdominal pain Ladd procedure 2005 Sato, et al. Hokkaido Surg J (in Japanese) 18 M abdominal pain release of ileus 2005 Kamiyama, et al. Radiat Med 14 M abdominal pain Ladd procedure 2007 Vechvitvarakul, et al. J Pediatr Surg 13 M abdominal pain, nausea, vomiting Ladd procedure, appendectomy 2007 Kusuda, et al. J Abdominal Emergency Medicine (in Japanese) 17 M abdominal pain Ladd procedure 2007 Draus, et al. Am Surg 17 F abdominal pain, nausea laparoscopic Ladd procedure 2008 Duran, et al. Turk J Gastroenterol 17 F abdominal pain division of adhesions 2008 Uchida, et al. J Pediatr Surg 13 F vomiting Bypass 2009 Fukushima, et al. Jpn J Endosc Surg (in Japanese) 15 F abdominal pain, distention laparoscopic Ladd procedure 2009 Tazaki, et al. J Abdominal Emergency Medicine (in Japanese) 14 M abdominal pain, vomiting release of ileus 2009 Shimodaira, et al.