And our results confirmed that the prevalence of CAFs was closely associated with the metastatic potential of gastric cancer, and further work should be done to confirm the correlation between CAFs’ prevalence and survival GSK126 of gastric cancer patients. Conclusions Our findings report here demonstrate that reactive cancer associated fibroblasts (CAFs) were frequently accumulated in gastric cancer tissues, and the prevalence of CAFs was correlated with tumor size, depth of the tumor and tumor metastasis as well as the overall TNM stage, suggesting that CAFs were critical for tumor growth, invasion and metastasis, thus give some supports for the prognosis of
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