Arch Surg 1990,125(10):1309–15.PubMed 30. Hypertonic versus near isotonic crystalloid for fluid resuscitation in critically ill patients Cochrane Database of Systematic Reviews 4 2004. 31. Kreimeier U, Christ F, Frey L, Habler O, Thiel M, Welte M, Zwissler B, Peter K: Small-volume resuscitation for hypovolemic shock. Concept, experimental and clinical results. Anaesthesist 1997,46(4):309–28.IPI-549 supplier CrossRefPubMed 32. Wade CE,

Kramer GC, Grady JJ, Fabian TC, Younes RN: Efficacy of hypertonic 7,5% saline and 6% dextran-70 in treating trauma: a meta-analysis MK-1775 order of controlled clinical studies. Surgery 1997,122(3):609–16.CrossRefPubMed 33. Wade CE, Grady JJ, Kramer GC, Younes RN, Gehlsen K, Holcroft JW: Individual patient cohort analysis of the efficacy of hypertonic saline/dextran in patients with traumatic brain injury and hypotension. J Trauma 1997,42(5):S61–65.CrossRefPubMed 34. Cooper DJ, Myles PS, McDermott FT, Murray LJ, Laidlaw J, Cooper G, Tremayne

AB, Bernard SS, Ponsdorf J: Prehospital hypertonic saline resuscitation of patients with hypotension and severe traumatic brain injury. JAMA 2004,291(11):1350–57.CrossRefPubMed 35. Doyle JA, Davis DP, Hoyt selleck DB: The use of hypertonic saline in the treatment of traumatic brain injury: a review. J Trauma 2001,50(2):367–83.CrossRefPubMed 36. Wade CE, Grady JJ, Kramer GC: Efficacy of hypertonic saline dextran fluid resuscitation for patients with hypotension from penetrating trauma. J Trauma 2003, 54:S144–48.PubMed 37. Rotstein OD: Novel strategies for immunomodulation after trauma: Revisiting hypertonic saline as a resuscitation strategy for hemorrhagic shock. J Trauma 2000, 49:580–583.CrossRefPubMed Competing interests The authors declare that they have no competing interests. Authors’ contributions JR,

VL, AK and AL have been participating in the study design. JR, VL and AK have been participating in the data collecting on field. MJ performed the data collection from the patient files, performed the statistical analysis and completed the manuscript with the support of AL. All authors have read and approved the Mannose-binding protein-associated serine protease final manuscript.”
“Introduction Intra-abdominal infections (IAI) include many pathological conditions, ranging from uncomplicated appendicitis to faecal peritonitis. IAI are classified into uncomplicated and complicated [1]. In uncomplicated IAIs the infectious process only involves a single organ and does not proceed to peritoneum. Patients with such infections can be managed with either surgical resection alone, or with antibiotics alone. When the focus of infection is treated effectively by surgical excision, 24 hours perioperative prophylaxis is sufficient. Patients with intra-abdominal infection, including acute diverticulitis and certain forms of acute appendicitis, may be managed nonoperatively.