Furthermore, there was no significant difference in the absolute carbohydrate intake between the diets, so e.g. muscle glycogen content should not have been lower after LPVD. Nonetheless, it seems that the vegetarian diet altered the need for oxygen during submaximal cycling. Since there were no differences in VO2max or time until exhaustion between the diet groups the implications

of the higher oxygen consumption at submaximal stages for maximal aerobic performance remains unclear. Conclusions A low-protein vegetarian diet followed for 4 days had no acute effect on venous blood acid–base status in young recreationally active men when compared to the normal diet of the subjects. The vegetarian diet increased VO2 during submaximal aerobic selleck kinase inhibitor cycling suggesting that the submaximal cycling economy was poorer after NSC 683864 purchase LPVD compared to ND. However, this had no further effect on maximal aerobic performance. According to these results, a low-protein vegetarian diet cannot be recommended as a means to improve submaximal or maximal aerobic performance via acid–base balance

as opposed to what was hypothesized. More studies are needed to define how nutrition, its comprehensive composition, and the duration of the diet period affect acid–base balance and performance. More specific measurements should also be used to determine the underlying mechanisms for higher VO2 after the low-protein vegetarian diet. Acknowledgements The authors would like to thank Rebekka Turkki for analyzing all the food diaries and Simon Walker for writing selleck chemical assistance. References 1. Adrogué HE, Adrogué HJ: Acid–base physiology. Respir Care www.selleck.co.jp/products/pazopanib.html 2001,46(4):328–341.PubMed 2. Vormann J, Goedecke T: Acid–base homeostasis: Latent acidosis as a cause of chronic diseases. Ganzheits Medizin 2006, 18:255–266.CrossRef 3. Lindinger MI: Origins of [H+] changes in exercising skeletal muscle. Can J Appl Phys 1995,20(3):357–368.CrossRef 4. Weinstein Y, Magazanik A, Grodjinovsky A, Inbar O, Dlin RA, Stewart PA: Reexamination of Stewart’s

quantitative analysis of acid–base status. Med Sci Sports Exerc 1991,23(11):1270–1275.PubMed 5. Kellum JA: Determinants of blood pH in health and disease. Crit Care 2000,4(1):6–14.PubMedCrossRef 6. Remer T: Influence of nutrition on acid–base balance – metabolic aspects. Eur J Nutr 2001, 40:214–220.PubMedCrossRef 7. Remer T, Dimitriou T, Manz F: Dietary potential renal acid load and renal net acid excretion in healthy, free-living children and adolescents. Am J Clin Nutr 2003, 77:1255–1260.PubMed 8. Robergs RA, Ghiasvand F, Parker D: Biochemistry of exercise-induced metabolic acidosis. Am J Phys – Reg I 2004, 287:R502-R516. 9. Mero AA, Keskinen KL, Malvela MT, Sallinen JM: Combined creatine and sodium bicarbonate supplementation enhances interval swimming. J Strength Cond Res 2004, 18:306–310.PubMed 10.