Improving the physicians’ work environment will likely require a reorganization of medical processes.”
“Irradiation by 30 keV Ga(+) ions was used to create defects in multiwalled carbon nanotubes. Damage to the graphitic structure of the nanotube wall resulting from ion irradiation was observed by a transmission electron microscope which was accompanied by corresponding changes in Raman spectra. It was found that ion irradiation at 2
x 10(13) ions/cm(2) cumulative dose increases the electric double layer capacitance of a multiwalled carbon nanotube electrode by a factor of 2.3, followed by a LY3039478 decrease and saturation at higher (2 x 10(14) and 4 x 10(14) ions/cm(2)) doses. This might be a trade-off between the enhancement caused by the tip opening and lowering of the capacitance due to amorphization of carbon nanotubes. (c) 2011 American Institute of Physics. [doi:10.1063/1.3553448]“
“Exposure to the industrial solvent, styrene, induces locomotor and cognitive dysfunction in rats, and parkinsonian-like manifestations
in man. The antipsychotic, haloperidol (HP), well known to induce striatal toxicity in man and animals, and styrene share a common metabolic pathway yielding p-fluoro phenylglyoxylic acid and phenylglyoxylic acid (PGA), respectively. Using an exposure period of 30 days and the vacous chewing movement (VCM) model as an expression of striatal-motor Fer-1 in vitro toxicity, we found that incremental PGA dosing (220-400 mg/kg) significantly increased VCMs up to day 25, but decreased to control levels shortly after reaching maximum dose. However, a diminishing dose of PGA (400-200 mg/kg) did not evoke an immediate worsening of VCMs but precipitated a significant
increase in VCMs following dosage reduction to 200 mg/kg on day 22. PGA exposure, therefore, compromises striatal-motor function that is especially sensitive to changes in exposure dose. Longer alternating dose exposure studies are needed to establish whether motor dysfunction is progressive in severity or longevity. These findings are of significance for the environmental toxicology of styrene in the chemical industry.”
“The frequency and intensity of menopausal symptoms within a given population, as assessed by several MLN2238 mouse tools, may vary and depend on several factors, such as age, menopausal status, chronic conditions and personal and partner socio-demographic profile.
To determine the frequency and intensity of menopausal symptoms and related risk factors among middle-aged women.
In this cross-sectional study a total of 404 women aged 40 to 59 years, visiting inpatients at the Enrique C. Sotomayor Gynecology and Obstetrics Hospital, Guayaquil, Ecuador, were requested to fill out the menopause rating scale (MRS) and a questionnaire containing personal and partner data.
Mean age of surveyed women (n = 404) was 48.2 +/- A 5.7 years, 85.1% had 12 or less years of schooling and 44.8% were postmenopausal.